Boston skyline at night

A MEDICAL THRILLER SERIES


Macrae Mysteries Book Cover

Point Mutation

"It's a fact of life that patients die in the ER. But not like this. When the beleaguered but brilliant Dr. Macrae fails to save a 30-year-old patient who dies in front of him, he can't let it go. And when the widow has more questions than answers, it sets Macrae on a collision course with the dark side of science and the money that funds it.

Finding the truth will take all he has because tracking him now are a pair of ex-military mercenaries and a killer with everything to lose. Soon Macrae is investigating more than he bargained for and wondering if the next one to die might be him."

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The Series

Book 1: Point Mutation

"When Macrae arrived for his shift that morning he had no idea he would pronounce someone dead. It wasn't uncommon in the ER. It happened, just not every day. Grandpa got rushed to the hospital after being found in his pajamas on the bathroom floor, or grandma just wouldn't wake up. Only this one was different because thirty-year-olds didn't die in his ER unless they wrapped themselves around a telephone pole or found the bottle of Oxycontin. They didn't die like this."

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Book 2: Twisted Helix

"When Macrae arrived for his shift that morning he had no idea he would pronounce someone dead. It wasn't uncommon in the ER. It happened, just not every day. Grandpa got rushed to the hospital after being found in his pajamas on the bathroom floor, or grandma just wouldn't wake up. Only this one was different because thirty-year-olds didn't die in his ER unless they wrapped themselves around a telephone pole or found the bottle of Oxycontin. They didn't die like this."

Coming 2026

About the Author

David Grayzel

David Grayzel is a physician, biotech entrepreneur, and accidental venture capitalist. After studying creative writing at Stanford, he got his MD at Harvard and completed his residency at Mass General Hospital.

Compelled by the opportunity to discover new medicines, he has been CEO of several successful biotechnology companies and helped launch many others with pursuits ranging from migraine prevention to gene therapy for cancer. He is currently a Partner at Atlas Venture focused on creating the next generation of innovative medicines.

His first novel, “Point Mutation,” is rooted in his decades of experience in medicine, and his lifelong admiration of The Simple Art of Murder.

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